Unregulated Expression of the Imprinted Genes H19 and Igf2r in Mouse Uniparental Fetuses Running Title: Imprinted Genes in Mouse Uniparetnal Fetuses
نویسندگان
چکیده
1 Department of Animal Science, Tokyo University of Agriculture, 1737, Funako, Atsugi, Kanagawa 243-0034, Japan, 2 Gene Research Center, Gunma University, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan, 3 Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, 1,111, Yata, Mishima, Shizuoka 411-8540, Japan, and 4 Department of BioScience, Tokyo University of Agriculture, 1-1-1, Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan
منابع مشابه
Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses.
The present study shows that the H19 and Igf2r genes, which are imprinted and expressed solely from maternal alleles, are expressed in an unregulatable manner in mouse uniparental, androgenetic, and parthenogenetic fetuses at day 9.5 of gestation. In the androgenetic fetuses, the H19 and Igf2r genes were respectively expressed at 12 and 40% of the levels in biparental fetuses. In addition, the ...
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